Dr. JORGE EMMANUEL SÁNCHEZ RODRÍGUEZ
Resumen curricular:
Licenciado en Física y Maestro en Ciencias en Física por la Universidad de Guadalajara, México, con estudios de Doctorado en Ciencias (Física) por el Instituto de Física de la UASLP, México. Realizó una estancia posdoctoral por 5 años en la prestigiosa Universidad de Chicago, USA. Desde el año 2015 es profesor investigador adscrito al Departamento de Física del CUCEI-UdeG donde dirige el laboratorio de investigación de Biofísica Molecular. Sus líneas de investigación se relacionan con el estudio molecular que generan los procesos dependientes del voltaje de proteínas de la membrana celular conocidas como canales iónicos. Para entender como la estructura de ese tipo de proteínas genera su función implementa metodologías vanguardistas que combinan procedimientos de Electrofisiología, Fluorometría, Biología Molecular y Modelaje. El Dr. Sánchez-Rodríguez forma parte del núcleo académico de los programas de la Licenciatura Física y del posgrado de la Maestría y Doctorado en Ciencias en Física del CUCEI-UdeG. Realiza colaboraciones internacionales y nacionales con investigadores adscritos al Hospital General de Massachusetts, Escuela de Medicina de la Universidad de Harvard, Institutos Nacionales de Salud (NIH, USA) y del Instituto de Física de la UASLP.
Perfil de Investigador SNII:
Perfil PRODEP:
Bases de datos bibliográficas:
Publicaciones del académico:
- Chemical and biophysical characterization of novel potassium channel blocker 3-fluoro-5-methylpyridin-4-amine
- Synthesis and evaluation of trisubstituted 4-aminopyridine derivatives as potential PET tracers for demyelinated axons
- Chemical and biophysical characterization of novel potassium channel blocker 3-fluoro-5-methylpyridin-4-amine
- Scorpions, Science and Folklore in Durango City
- Electro-steric opening of the clc-2 chloride channel gate
- Electro-steric opening of the clc- 2 chloride channel gate
- Electro-steric mechanism of CLC-2 chloride channel activation
- Structure-activity relationship studies of four novel 4-aminopyridine K+ channel blockers
- Novel 11C-labeled tracer for K+ channels in the brain: synthesis and imaging in non-human primates
- Strategies for the radiochemical synthesis of 11C-labeled 2-and 3-trifluoromethyl-4-aminopyridine: Potential radioligands for imaging brain demyelination
- Development of a PET radioligand for potassium channels to image CNS demyelination
- LRET determination of molecular distances during pH gating of the mammalian inward rectifier Kir1. 1b
- LRET Determination of Molecular Distances during pH Gating of the Mammalian Inward Rectifier Kir1.1b
- Ion Binding and Charge Movements in the Function of the Na/K-Pump
- Tuning Voltage Dependent Transitions during the Extracellular Na+ Binding/Release of the Na+/K+-ATPase by External Protons
- β1-subunit–induced structural rearrangements of the Ca2+-and voltage-activated K+ (BK) channel
- [18F] 3F4AP: a new PET tracer for brain demyelination
- Latex allergy in a paediatric hospital. Characteristics and risk factors Alergia al látex en un hospital pediátrico. Caracterización y factores de riesgo
- β1-subunit-induced structural rearrangements of the Ca2+- and voltage-activated K+ (BK) channel
- Fluorinated 4-aminopyrdines as PET tracers for MS
- A structural rearrangement of the Na+/K+-ATPase traps ouabain within the external ion permeation pathway
- Voltage Dependent Conformational Changes of the Na+/K+-ATPase Revealed by Site Directed Fluorometry
- Trypanosoma cruzi burden, genotypes, and clinical evaluation of Chilean patients with chronic Chagas cardiopathy
- LICENCIADO EN CIENCIAS C/M EN BIOLOGÍA, UNIVERSIDAD DE CHILE
- A Structural rearrangement of the Na+/K+-ATPase traps ouabain within the external ion permeation pathway
- Fluorinated 4-aminopyridines as PET tracers for multiple sclerosis
- Development of a PET tracer for MS
- Conformational Rearrangements of the Na+/K+ ATPase During Na+ Occlusion/Deocclusion Transitions Assessed by Site-Directed Fluorescence
- Probing Conformational Changes of the Na+/K+ ATPase upon Ouabain Binding by using a Spectroscopic Approach
- External Architecture of the Large-Conductance Ca2+ and Voltage-Activated K+ (BKCa) Revealed by a Spectroscopic Ruler
- Sequential interaction of chloride and proton ions with the fast gate steer the voltage-dependent gating in ClC-2 chloride channels
- Sequential interaction of chloride and proton ions with the fast gate steer the voltage‐dependent gating in ClC‐2 chloride channels
- Ouabain Binding Site in a Functioning Na plus/K plus-ATPase
- Changes of Intramolecular Distances in the Na+/K+ Atpase upon Ouabain Binding
- Ouabain binding site in a functioning Na+/K+ ATPase
- Detection of Trypanosoma cruzi in untreated chronic chagasic patients is improved by using three parasitological methods simultaneously
- Early steroid withdrawal in pediatric renal transplant: Five years of follow-up
- Permeant anions contribute to voltage dependence of ClC‐2 chloride channel by interacting with the protopore gate
- Simulating complex ion channel kinetics with IonChannelLab
- Permeant anions contribute to voltage dependence of ClC-2 chloride channel by interacting with the protopore gate
- Anomalous Mole Fraction Effect in ClC-2 Chloride Channel Pore
- Prevalence of drug abuse among children in basic schools Estudio de prevalencia del consumo de drogas en escolares de enseñanza básica, a través de la metodología de pares
- Gating and trafficking of ClC-2 chloride channel without cystathionine β-synthase domains
- Prediction of behavioral problems in chilean schoolchildren
- Enfermedad de Chagas crónica. Ausencia de Triatoma infestans intradomiciliario y persistencia de Trypanosoma cruzi circula
- Mental health study in two cohorts of schoolchildren from west Santiago. III: Early predictors of behavioral and cognitive problems
- Mental health study in two cohorts of schoolchildren from west Santiago. II: Family and school risk factors
- Mental health study in two cohorts of schoolchildren from west santiago. I: Prevalence and follow up of behavioral and cognitive problems