Dra. ANA MARÍA PUEBLA PÉREZ
Resumen curricular:
La Dra. Ana María Puebla Pérez es profesora del Centro Universitario de Ciencias Exactas e Ingenierías de la Universidad de Guadalajara. Es Química Farmacobióloga, Maestra en Biología Celular y Doctora en Inmunología. Es miembro del Sistema Nacional de Investigadores Nivel 2, y cuenta con 55 artículos JCR, además de un capítulo de libro. Sus líneas de Investigación son extracción, purificación y caracterización de metabolitos secundarios obtenidos de plantas medicinales mexicanas con potencial actividad anticancer, antiinflamatoria y antioxidante entre otras actividades que se resumen en la Farmacología e Inmunofarmacología de Productos Naturales y Sintéticos. En los productos sintéticos se pueden mencionar la síntesis enzimática de lignanos tipo podofilotoxina, y sus probables blancos terapéuticos.
Perfil de Investigador SNII:
Bases de datos bibliográficas:
Scopus
ORCID
Publicaciones del académico:
- Association of the rs8720 and rs12587 KRAS Gene Variants with Colorectal Cancer in a Mexican Population and Their Analysis In Silico
- Identificación por modelado molecular del efecto de Rutina presente en extractos de Siparuna Andina como antileishmaniásicoo
- Quimioinformática y Modelado Molecular de derivados tipo Podofilotoxina para el diseño de anticancerígenos
- SOD1 gene variants rs4817415, rs2070424, and rs1041740 and their association with breast cancer risk
- GC/MS Analysis, Antioxidant Activity, and Antimicrobial Effect of Pelargonium peltatum (Geraniaceae)
- Increased homocysteine plasma levels in breast cancer patients of a Mexican population
- TYMS 2R3R polymorphism and DPYD [IVS]14+1G > A gene mutation in Mexican colorectal cancer patients
- Antigiardial Activity of Podophyllotoxin-Type Lignans from Bursera fagaroides var. Fagaroides
- Artemisia dracunculus Extracts Obtained by Organic Solvents and Supercritical CO2 Produce Cytotoxic and Antitumor Effects in Mice with L5178Y Lymphoma
- Association of the Del1518 promoter (rs3730485) polymorphism in the MDM2 gene with breast cancer in a mexican population
- Association between TNF-α -308G>A and -238g>A gene polymorphisms and TNF-α serum levels in Mexican colorectal cancer patients
- Comprehensive analysis of venom from the scorpion Centruroides tecomanus reveals compounds with antimicrobial, cytotoxic, and insecticidal activities
- Effect of Artemisia dracunculus Administration on Glycemic Control, Insulin Sensitivity, and Insulin Secretion in Patients with Impaired Glucose Tolerance
- Association of the Alu insertion polymorphism in the progesterone receptor gene with breast cancer in a Mexican population
- Association of the C677T polymorphism in the methylenetetrahydrofolate reductase gene with breast cancer in a Mexican population
- Association of the GSTM1 null polymorphism with breast cancer in a mexican population
- Bioactive extracts of Citrus aurantifolia swingle seeds obtained by supercritical CO<inf>2</inf> and organic solvents comparing its cytotoxic activity against L5178Y leukemia lymphoblasts
- Association of the tumor necrosis factor-alpha -308G>A polymorphism with breast cancer in Mexican women
- Effects of the marine microalgae Isochrysis galbana and Nannochloropsis oculata in diabetic rats
- Intron 4 VNTR (4a/b) polymorphism of the endothelial nitric oxide synthase gene is associated with breast cancer in Mexican women
- Association between the Xba I polymorphism of APOB gene and plasma lipid level in Mexican patients with coronary artery disease
- Association of TP53 gene codon 72 polymorphism with endometriosis in Mexican women
- Cytotoxic podophyllotoxin type-lignans from the steam bark of Bursera fagaroides var. fagaroides
- The TP53 16-bp duplication polymorphism is enriched in endometriosis patients
- Effect of ditaxin and heteranthin and inhibitory effect of ditaxis heterantha extract on l5178Y Tumor development in mice
- Identification of immunodominant antigens of Mycobacterium bovis by expression library immunization
- Antitumor activity against murine lymphoma L5178Y model of proteins from cacao (Theobroma cacao L.) seeds in relation with in vitro antioxidant activity
- Antitumoral activity of allicin in murine lymphoma L5178Y
- Stereoselective enzymatic synthesis of monoglucosyl-myo-inositols with in vivo anti-inflammatory activity
- Apolipoprotein e genotypes in Mexican patients with Parkinson's disease
- Association of the 677C→T polymorphism in the MTHFR gene with colorectal cancer in Mexican patients
- An apology
- Bursera fagaroides, effect of an ethanolic extract on ornithine decarboxylase (ODC) activity in vitro and on the growth of Entamoeba histolytica
- CYP1A1 *2B and *4 polymorphisms are associated with lung cancer susceptibility in Mexican patients
- Distribution of CYP1A1*2A polymorphism in adult patients with acute lymphoblastic leukemia in a Mexican population
- Frequency of TS1494del6 polymorphism in colorectal patients from west of Mexico,Frecuencia del polimorfismo TS 1494del6 en pacientes con cáncer colorrectal del Occidente de México
- Polyamines as biomarkers of the antitumoral activity of Bursera fagaroides
- The MTHFR polymorphism C677T in adult patients with acute lymphoblastic leukemia is associated with an increased prevalence of cytogenetic abnormalities
- Cytochrome P4501A1 polymorphism is associated with susceptibility to acute lymphoblastic leukemia in adult Mexican patients
- Effect of Ginkgo biloba extract EGb 761 on the nonspecific and humoral immune responses in a hypothalamic-pituitary-adrenal axis activation model
- Effect of Ginkgo biloba extract, EGb 761, on the cellular immune response in a hypothalamic-pituitary-adrenal axis activation model in the rat
- Male rat infertility induction/spermatozoa and epididymal plasma abnormalities after oral administration of Kalanchoe gastonis bonnieri natural juice
- An experimental model of stress-induced immunosuppression produced by electrical stimulation of the brain in the rat
- Immunomodulatory activity of Chilean Cyttaria species in mice with L5178Y lymphoma